An event is experienced at multiple levels from sensory details to its meaning and significance. At encoding, all these aspects of a memory, and their neural correlates, are bound together into a memory trace or engram. With time and experience, as well as task demands, different aspects of the event are retained, transformed and modified, leading to memory reorganization. We think this term captures the nature of the processes at both psychological and neural levels better than memory consolidation. In this talk, I will describe some of the interactions between the hippocampus and neocortex, particularly the posterior neocortex and medial prefrontal cortex, that underlie memory reorganization and representation from before acquisition to long-term retention.

B05 PI Christoph Ploner will introduce, and Speaker Matthew Larkum will moderate the talk.

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