Projects
Publications
Layer 6b controls brain state via apical dendrites and the higher-order thalamocortical system
Timothy Adam Zolnik, Anna Bronec, Annemarie Ross, Marcel Staab, Robert N S Sachdev, Zoltán Molnár, Britta Johanna Eickholt, Matthew Evan Larkum
Neuron. 6;112(5):805-820.e4 (2024)
Bimodal dendritic processing in basket cells drives distinct memory-related oscillations
Alexandra Tzilivaki, Matthew Evan Larkum, Dietmar Schmitz
bioRxiv (2024)
The neural mechanisms of fast versus slow decision-making
Mostafa Nashaat, Hatem Oraby, Flutra Krasniqi, Sek Teng Goh-Sauerbier, Marion Bosc, Sandra Koerner, Sedef Karayel, Adam Kepecs, Matthew E. Larkum
bioRxiv (2024)
Layer 1 of somatosensory cortex: an important site for input to a tiny cortical compartment
Julia M T Ledderose, Timothy A Zolnik, Maria Toumazou, Thorsten Trimbuch, Christian Rosenmund, Britta J Eickholt, Dieter Jaeger, Matthew E Larkum, Robert N S Sachdev
Cereb Cortex. 33(23):11354-11372 (2023)
Presynaptic supervision of cortical spine dynamics in motor learning
Jaerin Sohn, Mototaka Suzuki, Mohammed Youssef, Sayuri Hatada, Matthew E. Larkum, Yasuo Kawaguchi and Yoshiyuki Kubota
Sci. Adv. 8,eabm0531 (2022)
The guide to dendritic spikes of the mammalian cortex in vitro and in vivo
Matthew E. Larkum, Jiameng Wu, Sarah A. Duverdin and Albert Gidon
Neuroscience 489:15–3 (2022)
Post-encoding modulation of spatial memory consolidation by propofol
Deetje Iggena, Patrizia M. Maier, Sophia M. Häußler, Mario Menk, Heidi Olze, Matthew E. Larkum, Carsten Finke, Christoph J. Ploner
Cortex 156, 1-12 (2022)
Are Dendrites Conceptually Useful?
Matthew E. Larkum
Neuroscience. 1;489:4-14 (2022)
Deep tissue scattering compensation with three-photon F-SHARP
Caroline Berlage, Malinda Tantirigama, Mathias Babot, Diego Di Battista, Clarissa Whitmire, Ioannis N. Papadopoulos, James F. A. Poulet, Matthew Larkum, Benjamin Judkewitz
Optica. 8:1613-1619 (2021)
Double-μ Periscope: a tool for multi-layer optical recordings, optogenetic stimulations or both
Mototaka Suzuki, Jaan Aru and Matthew E. Larkum
eLife 10:e72894 (2021)
Memories off the top of your head
Jiyun N. Shin, Guy Doron, Matthew E. Larkum
Science. 374: 6567 (2021)
Thalamic input to motor cortex facilitates goal-directed action initiation
Naoya Takahashi, Sara Moberg, Timothy A. Zolnik, Julien Catanese, Robert N.S. Sachdev, Matthew E. Larkum, Dieter Jaeger
Curr Biol. 31(18):4148-4155.e4 (2021)
Layer 6b is driven by intracortical long-range projection neurons
Timothy A. Zolnik, Julia Ledderose, Maria Toumazou, Thorsten Trimbuch, Tess Oram, Christian Rosenmund, Britta J. Eickholt, Robert N.S. Sachdev, Matthew E. Larkum
Cell Rep. 30(10):3492-3505.e5 (2020)
Perirhinal input to neocortical layer 1 controls learning
Guy Doron, Jiyun N Shin, Naoya Takahashi, Moritz Drüke, Christina Bocklisch, Salina Skenderi, Lisa de Mont, Maria Toumazou, Julia Ledderose, Michael Brecht, Richard Naud and Matthew E Larkum
Science. 370(6523):eaaz3136
Up and down states across somatosensory, entorhinal, and hippocampal cortices
John J Tukker, Prateep Beed, Dietmar Schmitz, Matthew E Larkum and Robert NS Sachdev
Front Syst Neurosci. 14:22 (2020)
Perspective on the multiple pathways to changing brain states
Malinda LS Tantirigama, Timothy Zolnik, Benjamin Judkewitz, Matthew E. Larkum and Robert NS Sachdev
Front Syst Neurosci. 14:23 (2020)
Active dendritic currents gate descending cortical outputs in perception
Naoya Takahashi, Christian Ebner, Johanna Sigl-Glöckner, Sara Moberg, Svenja Nierwetberg and Matthew E Larkum
Nat Neurosci. 23(10):1277-1285 (2020)
General anesthesia decouples cortical pyramidal neurons
Mototaka Suzuki and Matthew E Larkum
Cell. 180(4):666-676.e13 (2020)
Dynamic conjugate F-SHARP microscopy
Ioannis N Papadopoulos, Jean-Sebastien Jouhanneau, Naoya Takahashi, David Kaplan, Matthew Larkum, James Poulet and Benjamin Judkewitz
Light Sci Appl. 9:110 (2020)
Effects of sexual experience and puberty on mouse genital cortex revealed by chronic imaging
Johanna Sigl-Glöckner, Eduard Maier, Naoya Takahashi, Robert Sachdev, Matthew Larkum, Michael Brecht
Curr Biol. 29(21):3588-3599.e4 (2019)
Whisking asymmetry signals motor preparation and the behavioral state of mice
Sina E Dominiak, Mostafa A Nashaat, Keisuke Sehara, Hatem Oraby, Matthew E Larkum, and Robert NS Sachdev
J Neurosci. 39(49):9818-9830 (2019)
Cellular mechanisms of conscious processing
Jaan Aru, Mototaka Suzuki and Matthew E Larkum
Trends Cogn Sci. 24: 814-825 (2020)
Fast, flexible closed-Loop feedback: tracking movement in “real-millisecond-time”
Keisuke Sehara, Viktor Bahr, Ben Mitchinson, Martin J Pearson, Matthew E Larkum and Robert NS Sachdev
eNeuro. 6(6):ENEURO.0147-19.2019